Infliximab therapy in pediatric Crohn’s disease: a review
نویسندگان
چکیده
منابع مشابه
Infliximab therapy in pediatric Crohn’s disease: a review
Anti-tumor necrosis factor alpha (TNF-α) therapy has re-defined our treatment paradigms in managing patients with Crohn's disease (CD) and ulcerative colitis. Although the ACCENT studies showed proven efficacy in the induction and maintenance of disease remission in adult patients with moderate to severe CD, the pediatric experience was instrumental in bringing forth the notion of "top-down" th...
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nflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), has become one of the most common chronic conditions all over the world. The prevalence of IBD is growing rapidlyin developing countries along with nutrition transition. IBD affects children as well as adults, with 15-20% of patients being diagnosed during childhood. The onset of disea...
متن کاملAcupuncture Use In Pediatric Disease: A Short Review
Abstract: Acupuncture is increasingly used in children; however, the safety of pediatric acupuncture has yet to be reported from systematic review. Acupuncture has become a dominant complementary and alternative modality in clinical practice today but its associated risk has been questioned. The National Institutes of Health Consensus Statement states “one of the advantages of acupuncture is th...
متن کاملShort-Term Outcome of Infliximab Therapy in Pediatric Crohn's Disease: A Single-Center Experience
Purpose Studies on the efficacy of infliximab (IFX) in a large population of pediatric patients with Crohn's disease (CD) are limited, and prognostic factors are not well-known. The aim of this study was to evaluate outcomes of IFX in pediatric patients with CD and to identify factors associated with poor prognosis. Methods We retrospectively analyzed medical data of 594 pediatric patients wi...
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AIM To perform a systematic review and meta-analysis on the efficacy and tolerance of infliximab in ulcerative colitis. METHODS SELECTION OF STUDIES evaluating efficacy of infliximab in ulcerative colitis. For the meta-analysis, randomized clinical trials comparing infliximab vs. placebo/steroids. SEARCH STRATEGY electronic and manual. Study quality: independently assessed by two reviewe...
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ژورنال
عنوان ژورنال: Clinical and Experimental Gastroenterology
سال: 2010
ISSN: 1178-7023
DOI: 10.2147/ceg.s6451